Publications

Veterinary

Horse SAA

■ Jacobsen S and Andersen PH. The acute phase protein serum amyloid A (SAA) as a marker of inflammation in horses. EqVet Educ 2007;19:38–46. BEVA >

● Jacobsen S, et al. Validation of an equine serum amyloid A assay with an unusually broad working range. BMC Vet Res. 2019;15(1):462. PubMed >

● Kiemle J, et al. Comparison of a point-of-care serum amyloid A analyzer frequently used in equine practice with 2 turbidimetric immunoassays used in human and veterinary medicine. J Vet Diagn Invest. 2022 Jan; 34(1): 42–53. PubMed>

● Jacobsen S. Use of serum amyloid A in equine medicine and surgery. Vet Clin Pathol. 2023 Feb:52 Suppl 1:8-18. PubMed>

Cat SAA

● Waugh EM, et al. Validation of an automated immunoturbidimetric assay for feline serum amyloid A. BMC Vet Res. 2022;18(1):359. PubMed >

● Rossi G. Acute phase proteins in cats: Diagnostic and prognostic role, future directions, and analytical challenges. Vet Clin Pathol. 2023 Feb:52 Suppl 1:37-49. 
PubMed>

● Kurtz M, et al. Usefulness of serum amyloid A for the diagnosis of pyelonephritis in cats: A prospective evaluation. J Vet Intern Med. 2024 May-Jun;38(3):1542-1552. PubMed>

● Yuki M, et al. Comparison of polyclonal and monoclonal antibody assays for serum amyloid A in cats: a study based on an automated turbidimetric immunoassay in a primary care veterinary hospital. Am J Vet Res. 2024, Jul 12:1-6. PubMed>

Dog SAA

★ Christensen M, et al. Canine serum amyloid A (SAA) measured by automated agglutination turbidimetry is useful for routine sensitive and specific detection of systemic inflammation in a general clinical setting. J Vet Med Sci. 2013;75:459–466.    PubMed >

★ Christensen M, et al. Comparison of serum amyloid A and C-reactive protein as diagnostic markers of systemic inflammation in dog. Can Vet J, 55. 2014; 161-168.   PubMed >

★ Viitanen SJ, et al. The utility of acute-phase proteins in the assessment of treatment response in dogs with bacterial pneumonia. J Vet Intern Med 2017;31:124–33.   PubMed >

★ Löfqvist K, et al. Usefulness of C-reactive protein and serum amyloid A in early detection of postoperative infectious complications to tibial plateau leveling osteotomy in dogs. Acta Vet Scand. 2018;60:30.   PubMed >

● Behling-Kelly E, et al. Acute phase protein response and changes in lipoprotein particle size in dogs with systemic inflammatory response syndrome. [published online ahead of print, 2022 Apr 14]. J Vet Intern Med. 2022;10.1111/jvim.16420.   PubMed >

● Goggs R, et al. Serial analysis of blood biomarker concentrations in dogs with pneumonia, septic peritonitis, and pyometra. J Vet Intern Med. 2022;36(2):549-564.     PubMed >

● Takahashi K, et al.  Therapeutic effect of aged garlic extract on gingivitis in dogs. Front. Vet. Sci. 2023;1277272.   PubMed>

Rabbit SAA

● Lennox A, et al. Preliminary evaluation of an immunoturbidimetric assay and lateral flow device for the measurement of serum amyloid A in rabbits. Journal of Exotic Pet Medicine. Volume 33, April 2020, Pages 54-56    Science Direct >

Bovine SAA

● Otsuka M, et al. Sequential changes in hepatic mRNA abundance and serum concentration of serum amyloid A in cattle with acute inflammation caused by endotoxin. J Vet Med Sci. 82(7): 1006–1011, 2020.  PubMed >

● Sasazaki N, et al. Effects of dietary feed supplementation of heat-treated Lactobacillus sakei HS-1 on the health status, blood parameters, and fecal microbial flora of Japanese Black calves. J Vet Med Sci. 2020 Oct 20;82(10):1428-1435. PubMed>

● Otsuka M, et al. Diagnostic utility of measuring serum amyloid A with a latex agglutination turbidimetric immunoassay in bovine mastitis: comparison with haptoglobin and alpha 1 acid glycoprotein. J Vet Med Sci. 83(2): 329–332, 2021.  J-Stage >

● Okawa H, et al. Association between Anti-Müllerian Hormone Concentration and Inflammation Markers in Serum during the Peripartum Period in Dairy Cows.
 Animals (Basel). 2021 Apr 26;11(5):1241. PubMed>

● Sasazaki N, et al. Mitigation of sterigmatocystin exposure in cattle by difructose anhydride III feed supplementation and detection of urinary sterigmatocystin and serum amyloid A concentrations. Arch Anim Breed. 2021 Jun 16;64(1):257-264. PubMed>

● Franco-M. L, et al. Changes in saliva proteins in cows with mastitis: A proteomic approach. Res Vet Sci, 2021 Nov:140:91-99. PubMed>

● Widodo OS, et al. Practical Application of Urinary Zearalenone Monitoring System for Feed Hygiene Management of a Japanese Black Cattle Breeding Herd-The Relationship between Monthly Anti-Müllerian Hormone and Serum Amyloid A Concentrations. Toxins(Basel). 2022 Feb 16;14(2):143. PubMed>

● Shinya U, et al. Serum Amyloid A Concentrations of Healthy and Clinically Diseased Japanese Black Breeding Cattle-Preliminary Measurements for Determining the Cut-Off Concentrations. Vet Sci. 2022 Apr 21;9(5):198. PubMed>

● Widodo OS, et al. Relationship Between Ovary Size and Anti-Müllerian Hormone Levels in Holstein-Friesian Cows. Front Vet Sci. 2022 Jun 13:9:828123. PubMed>

● Widodo OS, et al. Practical Application of a Urinary Zearalenone Monitoring System for Feed Hygiene Management of a Japanese Black Cattle Breeding Herd-Relevance to Anti-Müllerian Hormone and Serum Amyloid A Clarified from a Two-Year Survey. Toxins(Basel). 2023 Apr 30;15(5):317. PubMed>

● Shinya U, et al. Usefulness of Measuring Serum Amyloid A Concentration in Japanese Black Cattle in Clinical Practice. Vet Sci. 2023 Aug 17;10(8):528. PubMed>

● Sasazaki N, et al. Effects of dietary feed supplementation with heat-treated Lactobacillus sakei HS-1 on the health status, blood parameters, and fecal microbes of Japanese Black calves before weaning. Vet World. 2023 Nov;16(11):2293-2302. PubMed>

● Nielsen LN, et al. Performance of an automated immunoturbidimetric assay for bovine serum amyloid A. Vet Clin Pathol. 2024 Jun;53(2):229-233. PubMed>

Poultry SAA

● Kromann S, et al. Assessment of automated assays for serum amyloid A, haptoglobin (PIT54) and basic biochemistry in broiler breeders experimentally infected with Escherichia coli. Vet Res. 2022;53(1):25.    PubMed >

Other species SAA

● Edwards K L, et al. Patterns of serum immune biomarkers during elephant endotheliotropic herpesvirus viremia in Asian and African elephants. PLoS One. 2021 Nov 18;16(11):e0252175. PubMed>

● Hooijberg E H, et al. Acute phase reactants in nondomesticated mammals-A veterinary clinical pathology perspective. Vet Clin Pathol. 2023 Feb:52 Suppl 1:19-36. PubMed>

● Ijiri M, et al. Potential Biomarkers for Chronic Seasonal Heat Stress in Kagoshima Berkshire Pigs Reared in the Subtropical Region. J Vet Res. 2022 May 31;66(2):209-214. PubMed>

● Kimura T. Comparative evaluation of acute phase proteins by C-reactive protein (CRP) and serum amyloid A (SAA) in nonhuman primates and feline carnivores. Animal Diseases 2, 21 (2022). BMC>

● Edwards K L, et al. Patterns of serum immune biomarkers during elephant endotheliotropic herpesvirus viremia in Asian and African elephants. Vet Clin Pathol. 2023 Feb:52 Suppl 1:19-36.  PubMed>

★ Christensen M, et al. Evaluation of an automated assay based on monoclonal anti-human serum amyloid A (SAA) antibodies for measurement of canine, feline, and equine SAA. Vet J. 2012;194:332–337. PubMed>

Product Series

VET-SAA ‘Eiken’

VET-SAA ‘Eiken’ is a turbidimetric immunoassay reagent for measurement of serum amyloid A (SAA) in animal serum and plasma.

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